Guitar Lessons by Chip McDonald - R577X Polymorphism α-actnin-3 "Speed Gene": I was at least 70% Wrong In My Last Post!

Wednesday, May 8, 2019

R577X Polymorphism α-actnin-3 "Speed Gene": I was at least 70% Wrong In My Last Post!

  Ok, well... maybe speed isn't 100% up to how patient you are.

 I'm different than at least 30%, perhaps in a tiny fraction of the population.  When I was a kid there were some anomalies.  

 I could always run faster than anyone in the 3 schools I went to.  Not for long - but in 30 meters I would definitely be ahead.  The coaches wanted me to be on track team seeing me zip around playing football during p.e., but I knew I had zero endurance capability - doing 50 laps around the football field was always grueling.

 In BMX I never won any races.  In fact, I found it insanely difficult to keep power going through a whole race.  One of the few times I've passed out in my life was between heats in a BMX event.  BUT - I was always ahead of everyone into the first corner, despite having a very steep "wrong" gearing on my bike.

 In 5th grade I could leg press the entire amount of weight on the machine - at least 1 time. Which was more remarkable given I was almost the smallest guy in the school.  BUT - I did not have any special endurance at "normal" weights.

 Skateboarding came easy to me.  Anything fast and quick.  

 When I started playing guitar, I was instantly "fast".  I didn't find speed to be particularly challenging on guitar.   Playing an entire Sor piece from an endurance standpoint was different, probably a big reason I didn't pursue classical guitar, but preferred learning passages from classical violin pieces.

 My wife recently got us the 23andme genetic testing service for my birthday.  As it turns out I carry the R577 alpha actinin-3 "elite power athlete-sprinter gene": my muscle composition likely is more like 80% fast twitch/Type II fiber instead of 20%, versus "slow, endurance" Type I.  

 So it would seem I have an advantage that I suspected, but had no direct evidence of.  Additional bonuses of this polymorphism are recovery time and training response.  As an aside, I have always found my wife's muscle cramps to be rather... disturbing, kind of surreal.  Because - I've never had a muscle cramp.  I haven't read that that has something to do with R577X alpha-actinin-3, but I would suggest it probably does ("everyone" has muscle cramps?  Where the muscle just.. does stuff... by itself...?  Yikes).

 The flipside to this: I'm at a disadvantage for muscle fatigue!  So it's more likely doing those bar chord exercises are more difficult for you than me!  Then there is the variant that bestows endurance; which favors the classical guitarist greatly I would imagine, being able to do multiple hours of bar chord-form based effort. 

 All of this would follow my observations of giving guitar lessons. Of the Famous Guitar Players you know, there are the few that are in that "upper .1% speed" bracket. But here's the takeaway: it's more useful in a pragmatic, musician sense, to NOT have this gene!   

 Speed is not inherently artistic.  Nor is it particularly special today, as it has been allowed to become a trite gimmick. The person with the endurance variant is more likely to find that trait useful.  And given that the fatigue I get from holding bar chords for a long time is probably greater than the average population - that's a great disadvantage as a guitarist. 

 You now have an excuse not to be able to play "ultra fast", maybe... BUT - for the rest, you probably have an advantage over me!  So go practice!


1 comment:

  1. It is a very informative and useful post thanks it is good material to read this post increases my knowledge

    Guitar Setup